Protodioscin is a steroidal saponin found in Tribulus. Its main function is to increase testosterone levels in the body as well as the ability to be used as a sexual performance enhancer.
Proper testosterone levels are extremely important for men and unfortunately, they start to drop off as early as the age of 30—which can cause many health issues and concerns.
Protodioscin is responsible for stimulating the pituitary gland which can then produce Luteinizing Hormone (LH) and raise the level of testosterone present in the body.
Research has shown that protodioscin is so powerful, that it can increase testosterone levels by as much as 46%. In addition, there were improvements in sperm count, sperm morphology, libido, cardiovascular health, mental alertness, and mood.
Most importantly, research has found supplementing with protodioscin to be safe and extremely effective.
Absolutely! A quality Tribulus extract has a host of benefits for women including reproductive support, enhanced fertility, and regular menstrual cycles. In addition, just like with men, Tribulus does have libido-enhancing properties with women and increases sex drive due to its aphrodisiac properties.
In an open study, 98% of 50 menopausal women experienced symptom improvement after TLSE(TLSE, standardised to not less than 45% furostanol saponins calculated as protodioscin) treatment, but not after placebo. Fifty-two percent of patients were experiencing natural menopause and 48% had postoperative symptoms after removal of their ovaries. Predominant symptoms included hot flushes, sweating, insomnia and depression. The dosage prescribed varied, but generally a maintenance dose of 500–750 mg/day of TLSE was reached after higher initial doses. Treatment did not result in significant changes in FSH, LH, prolactin, oestradiol, progesterone and testosterone, although FSH tended to be lower.16
In an open study involving infertile women, TLSE (750– 1500 mg) was administered every day for 2–3 months (Group 1), only on days 5 to 14 of the menstrual cycle for 2–3 months (Group 2), or used in the preovulatory phase in combination with an ovulation stimulant for 3 months (Group 3).16 Group 1 did not show improvement in the ovulation parameters measured and side effects were observed, especially when the treatment was abruptly terminated. Of the 36 women in Group 2, 6% of women experienced normalised ovulation with resultant pregnancy, 61% demonstrated normalised ovulation without pregnancy and 33% demonstrated no effect from treatment. Parallel control studies on a comparable cohort were carried out utilising three ovulation stimulants. The best results were obtained with 62 women treated using epimestrol: 39% had normalised ovulation with pregnancy, 35% had normalised ovulation without pregnancy and 26% demonstrated no effect from treatment. No side effects were recorded for the TLSE group, compared with an incident rate of 6.5%, 10.6% and 38% in women treated with ovulation stimulants. For the 20 women treated with TLSE and an ovulation stimulant (Group 3), the effect from their combined use was better than treatment with either single agent.
Mechanism of Action Saponins
from Tribulus appear to increase FSH in women, which in turn increases levels of oestradiol. They may do this by binding with, but only weakly stimulating, hypothalamic oestrogen receptors, which are part of the negative feedback mechanism of oestrogen control. The weak stimulus (as opposed to oestrogen) leads the body to interpret that oestrogen levels are lower than they really are and it subsequently increases production. In the postmenopausal woman Tribulus might alleviate symptoms of oestrogen withdrawal by the binding of its steroids to vacant receptors in the hypothalamus (in this low oestrogen situation). This could be sufficient to convince the body that more oestrogen is present in the bloodstream than actually is. A similar mechanism via the hypothalamus could apply for men.
First and foremost, you need to look at a Tribulus product standardized to (a certain percentage of) protodioscin. Tribulus products rich in protodioscin have been shown to increase testosterone levels in men, which has many benefits including boosting testosterone production, improving sex life, and even increasing lean muscle mass and strength.
Boldanic Tribulyze was created based off the demand for a high quality Tribulus product—giving you the ability to naturally and effectively increase your levels of testosterone. With potent standardized (minimum 40% protodioscin) Tribulus Terrestris Extract, Boldanic Tribulyze is setting the industry standard for the Tribulus category.
We refuse to compromise when it comes to bringing you the best ingredients at efficacious dosages. You refuse to settle in the gym and strive to be the best, and we never want to let you down. What you see on the bottle is what you get. No guesswork. No funny business.
Our main objective was to come out with the best form of Tribulus to give you the results you desire. Unlike many products on the market, Tribulyze uses a minimum 40% protodioscin in its formula. Some brands that have been tested using miniscule amounts of protodioscin—ultimately not making any true difference in your testosterone levels. By supplementing with a laboratory tested and properly dosed Tribulus, like what is found in Tribulyze, you are able to boost your testosterone production. By improving hormone levels, you will notice a difference during your workouts. You’ll feel stronger, you’ll recover quicker, and you’ll increase the release of nitric oxide which can dilate the blood vessels—allowing nutrients to be shuttled quickly into the working muscles as well as giving you the desired pump you wish to achieve each and every workout.
From the benefits that can be had by supplementing with an extremely potent form of Tribulus, such as with Tribulyze, you’ll wonder why it took you so long to find this next level form of Tribulus. Try this industry-changing testosterone booster for yourself and FEEL the difference! Boldanic Tribulyze… Naturally STRONG.
1. Gauthaman K1, Ganesan AP, Prasad RN. Sexual effects of puncturevine (Tribulus terrestris) extract (protodioscin): an evaluation using a rat model. 2003 Apr;9(2):257-65.
2.Maheshwari A, Verma N, Swaroop A, Bagchi M, Preuss HG, Tiwari K, Bagchi D. Efficacy of FurosapTM, a novel Trigonella foenum-graecum seed extract, in Enhancing Testosterone Level and Improving Sperm Profile in Male Volunteers.2017 Jan 10;14(1):58-66. doi: 10.7150/ijms.17256. eCollection 2017.
3. Salgado RM, Marques-Silva MH, Gonçalves E, Mathias AC, Aguiar JG, Wolff P. IEffect of oral administration of Tribulus terrestris extract on semen quality and body fat index of infertile men.2017 Jun;49(5). doi: 10.1111/and.12655. Epub 2016 Jul 12.
4. Gauthaman K, Ganesan AP. The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction--an evaluation using primates, rabbit and rat.2008 Jan;15(1-2):44-54.
5. Carlos RB Gama, Ricardo Lasmar, Gustavo F Gama, Camila S Abreu, Carlos P Nunes, Mauro Geller Lisa Oliveira, Alessandra Santos. Clinical Assessment of Tribulus terrestris Extract in the Treatment of Female Sexual Dysfunction. 2014; 7: 45–50.